glp-1 leptin Schematic depicting the potential signaling cross-talk between leptin, JCI - Revisiting leptin's role

GOLO is the only diet that has truly proven to be a success for me

These drugs fall within two categories: human GLP-1 backbone agents (that is, albiglutide, dulaglutide, liraglutide and semaglutide) and exendin-4 backbone agents (that is, exenatide, lixisenatide and tirzepatidethe latter activating both GLP-1 and glucose-dependent insulinotropic polypeptide (GIP) receptors) 1

Resistance Training Protocol: 3-4 sessions per week of strength training stimulates muscle protein synthesis and offsets GLP-1's reduction in protein synthesis rates

Results vary significantly based on individual absorption and technique quality